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TL;DR

What it is
NMN precursor supplement for NAD+ and healthy aging support.
Who it’s for
Adults looking for daily nmn support as part of a consistent supplement routine.
Key ingredients
NMN

NMN

GMP
  • NMN precursor supplement for NAD+ and healthy aging support.
  • DIETARY SUPPLEMENT · 30 CAPSULES · 30-DAY SUPPLY

$44.99

NMN precursor supplement for NAD+ and healthy aging support.

SKU: SUF-NMN Category:

About NMN

NMN precursor supplement for NAD+ and healthy aging support.

Formulated with ingredients studied for their role in daily wellness. See research highlights below.

Part of these protocols

This compound is included in curated Protocol Labs stacks — save when you subscribe to the full routine.

Supplement facts

Supplement Facts
Serving Size 1 Capsule
Servings Per Container 30
Amount per serving % Daily Value
β-Nicotinamide Mononucleotide 500 mg

Other ingredients: HPMC (vegetable capsule), microcrystalline cellulose, silicon dioxide, magnesium stearate.

Net weight
1.6 oz / 0.1 lb / 45 g
Supply
DIETARY SUPPLEMENT · 30 CAPSULES · 30-DAY SUPPLY

How to use

As a dietary supplement, adults take one (1) capsule daily. For best results, take with 6–8 oz (177–237 ml) of water or as directed by healthcare professional.

Full ingredient list

β-Nicotinamide Mononucleotide (500 mg), HPMC (vegetable capsule), Microcrystalline Cellulose, Silicon Dioxide, Magnesium Stearate.

Warnings & storage
Do not exceed recommended dose. Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement. Keep out of reach of children. Do not use if safety seal is damaged or missing. Store in a cool, dry place.
Quality & fulfillment
  • GMP — verified on label
  • Ships from GMP-certified U.S. fulfillment partners
  • Private Protocol Labs label art applied at fulfillment

Research highlights

Published studies on key ingredients in this formula. Not intended as medical advice.

NMN Efficacy & Safety: Dose-Dependent RCT in Middle-Aged Adults

This multicenter, double-blind, placebo-controlled trial tested 300, 600, and 900 mg/day of NMN in 80 healthy adults aged 40–65 over 60 days. Blood NAD levels rose significantly and dose-dependently in all NMN groups compared to placebo, with 600 mg appearing to be the optimal dose. Participants taking NMN also walked farther in a 6-minute walking test, showed better quality-of-life scores, and maintained stable biological age while the placebo group's biological age increased. No adverse events were attributed to NMN at any dose.

View source

NMN Supplementation Enhances Aerobic Capacity in Amateur Runners

This 6-week, four-arm RCT tested 300, 600, and 1200 mg/day of NMN in 48 recreationally trained runners during a structured exercise program. NMN significantly improved the ventilatory threshold — a key marker of aerobic endurance — in a dose-dependent manner compared to exercise-plus-placebo. The benefit appeared to stem from enhanced oxygen utilization in skeletal muscle rather than improved cardiac function. No adverse events were reported at any dose.

View source

NMN Supplementation, NAD Metabolism & Arterial Stiffness

This 12-week, double-blind, placebo-controlled trial gave 250 mg/day of NMN to 36 healthy middle-aged Japanese adults. Serum nicotinamide — a downstream marker of NAD metabolism — rose significantly in the NMN group, confirming that NMN actively boosts NAD pathways in humans. Arterial stiffness (pulse wave velocity) showed a trend toward improvement in NMN users, particularly in those with higher BMI or blood glucose levels, though the difference did not reach statistical significance in the full group. The supplement was well-tolerated with no safety concerns over the 12-week period.

View source

Time-Dependent NMN Intake: Sleep, Fatigue & Physical Function in Older Adults

This 12-week RCT enrolled 108 Japanese adults aged 65 and older, comparing morning vs. afternoon NMN intake (250 mg/day) against placebo. Afternoon NMN intake produced the most meaningful improvements, significantly reducing drowsiness and improving lower-limb function (sit-to-stand performance) with moderate-to-large effect sizes. Sleep quality scores also showed a favorable trend in the afternoon NMN group, though without reaching statistical significance. The supplement was safe and well-tolerated across all groups, with intake compliance exceeding 95%.

View source

Common questions

How should I take NMN?

As a dietary supplement, adults take one (1) capsule daily. For best results, take with 6–8 oz (177–237 ml) of water or as directed by healthcare professional.

Can I pair this with a Protocol Labs stack?

Yes. This compound is available standalone or as part of curated protocol stacks. Check the "Part of these protocols" section for bundles that include it.

Where is this manufactured?

Protocol Labs products are fulfilled from GMP-certified U.S. facilities via vetted dropship partners. Each bottle ships with a printed supplement facts panel matching the formula listed on this page.

What is NMN used for?

NMN precursor supplement for NAD+ and healthy aging support. Consult your healthcare provider before use, especially if pregnant, nursing, or taking medications.

Is NMN FDA approved?

No. NMN is a dietary supplement, not an FDA-approved drug. It is not intended to diagnose, treat, cure, or prevent any disease.

Does Protocol Labs offer subscribe-and-save on NMN?

Subscribe-and-save is available on protocol stacks. Standalone compounds like NMN are typically sold as one-time purchases on protocollab.store.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

NMN precursor supplement for NAD+ and healthy aging support.

Formulated with ingredients studied for their role in daily wellness. See research highlights below.

Key ingredients

β-Nicotinamide Mononucleotide (500 mg), HPMC (vegetable capsule), Microcrystalline Cellulose, Silicon Dioxide, Magnesium Stearate.

Supplement Facts
Serving Size 1 Capsule
Servings Per Container 30
Amount per serving % Daily Value
β-Nicotinamide Mononucleotide 500 mg

Other ingredients: HPMC (vegetable capsule), microcrystalline cellulose, silicon dioxide, magnesium stearate.

NMN Efficacy & Safety: Dose-Dependent RCT in Middle-Aged Adults

This multicenter, double-blind, placebo-controlled trial tested 300, 600, and 900 mg/day of NMN in 80 healthy adults aged 40–65 over 60 days. Blood NAD levels rose significantly and dose-dependently in all NMN groups compared to placebo, with 600 mg appearing to be the optimal dose. Participants taking NMN also walked farther in a 6-minute walking test, showed better quality-of-life scores, and maintained stable biological age while the placebo group's biological age increased. No adverse events were attributed to NMN at any dose.

View source

NMN Supplementation Enhances Aerobic Capacity in Amateur Runners

This 6-week, four-arm RCT tested 300, 600, and 1200 mg/day of NMN in 48 recreationally trained runners during a structured exercise program. NMN significantly improved the ventilatory threshold — a key marker of aerobic endurance — in a dose-dependent manner compared to exercise-plus-placebo. The benefit appeared to stem from enhanced oxygen utilization in skeletal muscle rather than improved cardiac function. No adverse events were reported at any dose.

View source

NMN Supplementation, NAD Metabolism & Arterial Stiffness

This 12-week, double-blind, placebo-controlled trial gave 250 mg/day of NMN to 36 healthy middle-aged Japanese adults. Serum nicotinamide — a downstream marker of NAD metabolism — rose significantly in the NMN group, confirming that NMN actively boosts NAD pathways in humans. Arterial stiffness (pulse wave velocity) showed a trend toward improvement in NMN users, particularly in those with higher BMI or blood glucose levels, though the difference did not reach statistical significance in the full group. The supplement was well-tolerated with no safety concerns over the 12-week period.

View source

Time-Dependent NMN Intake: Sleep, Fatigue & Physical Function in Older Adults

This 12-week RCT enrolled 108 Japanese adults aged 65 and older, comparing morning vs. afternoon NMN intake (250 mg/day) against placebo. Afternoon NMN intake produced the most meaningful improvements, significantly reducing drowsiness and improving lower-limb function (sit-to-stand performance) with moderate-to-large effect sizes. Sleep quality scores also showed a favorable trend in the afternoon NMN group, though without reaching statistical significance. The supplement was safe and well-tolerated across all groups, with intake compliance exceeding 95%.

View source

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NMN $44.99